As greenhouse gas (GHG) concentrations continue to rise owing to natural and human factors, it triggers global warming causing phenomenal effects climate change, which has assumed a pervasive issue of global concern (UNFCCC. 2017; UNICEF. 2021) ^{[45, 46]}. Since agriculture is critical component of Nigeria's GDP, this study examines the multifaceted implication of climate change on her agro-economy, emphasizing the opportunities and obstacles for adaptation strategies. Water shortages, soil degradation, pest and disease proliferation, poor agricultural productivity, alarming food insecurity, low economic returns on agro-based investment, and capital loss have been triggered byclimate change. The study made extensive use of online resources, expert opinions, grey literature through thematic review and systematic assessment of resource materials about climate change. Exploring the tenets of vulnerability and diffusion of innovation theories, this study found that climate change has significantly reduced agricultural output and farmers revenues, especially in rural areas. Additional findings include worsening food insecurity, and multi-dimensional vulnerability, including exacerbating overall economic outlook in Nigeria. The study concludes that immediate policy changes are necessary to lessen the escalating effects of climate change in Nigeriain line with the assertion of World Health Organization (WHO, 2018). The study recommends community-based awareness drive, immediate adoption of climate-resilient smart agriculture methodology and incentives, improved seedlings and farm inputs as well as improved weather forecasting and early warning systems.